Caprin1 Polyclonal Antibody for Mouse(Mus musculus) | EIAab.comCaprin1 Polyclonal Antibody for Mouse(Mus musculus)

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Caprin1 (Gene name),

Caprin-1 (Protein name ), CAPR1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Caprin1(G5E5;Gpiap;Gpiap1;Gpip137;M11s1;Rng105);

Protein name:

Caprin-1;

Alternative:

GPI-anchored membrane protein 1;Cytoplasmic activation- and proliferation-associated protein 1;Membrane component chromosome 11 surface marker 1;GPI-anchored protein p137(GPI-p137;p137GPI);RNA granule protein 105;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

May form homomultimers. Directly interacts with G3BP1 in cytoplasmic RNA granules. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.

Function:

May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types.

Subcellular Location:

Cytoplasm cytosol Cell projection dendrite Associated with RNA granules.

Protein Attributes:

Sequence length:

707

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

707:

MNTQQVN

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q60865

UniGene:

Mm.337310

Pfam:

PF12287

KEGG:

mmu:53872

UniGene:

Mm.427589

Uniprot:

Q60865

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ELISA Kit for Mouse Caprin-1

Cat.:

E14581h

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96T

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ELISA Kit for Mouse Caprin-1

Cat.:

E14581r

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96T

ELISA Kit for Mouse Caprin-1

Cat.:

E14581b

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96T

ELISA Kit for Mouse Caprin-1

Cat.:

E14581m

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96T

CLIA Kit for Mouse Caprin-1

Cat.:

U14581h

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96T

CLIA Kit for Mouse Caprin-1

Cat.:

U14581b

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96T

CLIA Kit for Mouse Caprin-1

Cat.:

U14581m

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96T

CLIA Kit for Mouse Caprin-1

Cat.:

U14581r

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96T

Polyclonal Antibody for Mouse Caprin-1

Cat.:

P14581Rb-r

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40ug/0.2ml

Polyclonal Antibody for Mouse Caprin-1

Cat.:

P14581Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse Caprin-1

Cat.:

P14581Rb-m

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40ug/0.2ml

Monoclonal Antibody for Mouse Caprin-1

Protein for Mouse Caprin-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Novel cDNA clone, G5E5, isolated from a mouse neonatal cerebellar library is expressed in a variety of adult and neonatal tissues."
Hodes M.E.
Submitted (1995-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/6J-AW-J/AW-J X CBA/CAGNLE-A/A.
tissue: Cerebellum.
2.

"RNA granule protein RNG105 deficiency impairs the dendritic localization of Na+/K+ ATPase subunit isoforms and synapse formation."
Shiina N. , Tokunaga M.
Submitted (2007-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/6.
3.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
5.

"The gene encoding the GPI-anchored membrane protein p137GPI (M11S1) maps to human chromosome 11p13 and is highly conserved in the mouse."
Gessler M. , Klant B. , Tsaoussidou S. , Ellis J.A. , Luzio J.P.
Genomics32:169-170(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-362
strain: C57BL/6.
tissue: Embryo.
6.

"Novel cDNA clone, G5E5, maps to chromosome 16 and is expressed in a variety of adult and neonatal tissues."
Hodes M.E.
Submitted (1995-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 402-707
strain: C57BL/6J-AW-J/AW-J X CBA/CAGNLE-A/A.
tissue: Cerebellum.
7.

"Activation/division of lymphocytes results in increased levels of cytoplasmic activation/proliferation-associated protein-1: prototype of a new family of proteins."
Grill B. , Wilson G.M. , Zhang K.-X. , Wang B. , Doyonnas R. , Quadroni M. , Schrader J.W.
J. Immunol.172:2389-2400(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;PHOSPHORYLATION;MULTIMERIZATION
8.

"Distinct structural features of caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2alpha, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs."
Solomon S. , Xu Y. , Wang B. , David M.D. , Schubert P. , Kennedy D. , Schrader J.W.
Mol. Cell. Biol.27:2324-2342(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH G3BP1;SUBCELLULAR LOCATION
9.

"RNA granule protein 140 (RNG140), a paralog of RNG105 localized to distinct RNA granules in neuronal dendrites in the adult vertebrate brain."
Shiina N. , Tokunaga M.
J. Biol. Chem.285:24260-24269(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE

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